Cellosaurus cell line WCMC-37 (CVCL

Cross-references
Cell line name	WCMC-37
Synonyms	WCMC 37; WCMC37; WMC 37
Accession	CVCL_B919
Resource Identification Initiative	To cite this cell line use: WCMC-37 (RRID:CVCL_B919)
Comments	From: Weill Cornell Medical College; New York; USA. Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0211. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations	Mutation; HGNC; HGNC:3775; FMR1; Repeat_expansion; CGG[142-450]; Zygosity=Hemizygous (PubMed=24289922).
Disease	Fragile X syndrome (NCIt: C84717) Fragile X syndrome (ORDO: Orphanet_908)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	PubMed=24289922; DOI=10.1016/j.molcel.2013.10.029; PMCID=PMC3920742 Jeannine Gerhardt, Mark J. Tomishima, Nikica Zaninovic, Dilek Colak, Zi Yan, Qian-Sheng Zhan, Zev Rosenwaks, Samie R. Jaffrey, Carl L. Schildkraut; The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells. Mol. Cell 53:19-31(2014) PubMed=27690107; DOI=10.3390/genes7100077; PMCID=PMC5083916 Hagar Mor-Shaked, Rachel Eiges; Modeling fragile X syndrome using human pluripotent stem cells. Genes (Basel) 7:77.1-77.19(2016)
Cell line databases/resources	NIHhESC; NIHhESC-13-0211
Encyclopedic resources	Wikidata; Q54993669
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	21