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Cellosaurus ESI-049 (CVCL_B857)

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Cell line name ESI-049
Synonyms ESI049; SSCCe004-A
Accession CVCL_B857
Resource Identification Initiative To cite this cell line use: ESI-049 (RRID:CVCL_B857)
Comments Group: Clinical grade pluripotent cell line.
From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-11-0130.
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): ESI BIO

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135815,16
D5S81811,12
D7S82011,13
D8S117914,15
D13S31712,13
D16S5399,11
D18S5110,13
D21S1129,31
FGA18,20
Penta D11,15
Penta E15,18
TH019
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Web pages Provider; ESI BIO; ES-702; https://web.archive.org/web/20141201204330/http://www.esibio.com/esi-049-human-embryonic-stem-cell-line-46-xy/
Publications

PubMed=18371388; DOI=10.1016/j.stem.2007.10.004
Jeremy Micah Crook, Teija Tuulikki Peura, Lucy Kravets, Alexis Gina Bosman, Jeremy James Buzzard, Rachel Horne, Hannes Hentze, Norris Ray Dunn, Robert Zweigerdt, Florence Chua, Alan Upshall, Alan Colman;
The generation of six clinical-grade human embryonic stem cell lines.
Cell Stem Cell 1:490-494(2007)

PubMed=20177998; DOI=10.1007/s11626-010-9287-1
Shirani Sivarajah, Grace Selva Raj, Adam Joshua Varughese Mathews, Norliza Binte Esmail Sahib, Wei-Sek Hwang, Jeremy Micah Crook;
The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research.
In Vitro Cell. Dev. Biol. Anim. 46:210-216(2010)

PubMed=22265736; DOI=10.1016/j.scr.2011.10.001
Walter D. Funk, Ivan Labat, Janani Sampathkumar, Pierre-Antoine Gourraud, Jorge R. Oksenberg, Elen S. Rosler, Daniel Steiger, Nadia Sheibani, Stacy Caillier, Birgit Stache-Crain, Julie A. Johnson ...Show all 18 authors... , Lorraine Faxon Meisner, Markus Daniel Lacher, Karen B. Chapman, Myung Jin Park, Kyoung-Jin Shin, Radoje Drmanac, Michael D. West; Show fewer authors
Evaluating the genomic and sequence integrity of human ES cell lines comparison to normal genomes.
Stem Cell Res. 8:154-164(2012)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources hPSCreg; SSCCe004-A
NIHhESC; NIHhESC-11-0130
SKIP; SKIP002088
Encyclopedic resources Wikidata; Q54832759
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18