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Cellosaurus ESI-035 (CVCL_B856)

[Text version]
Cell line name ESI-035
Synonyms ESI035; SSCCe007-A
Accession CVCL_B856
Resource Identification Initiative To cite this cell line use: ESI-035 (RRID:CVCL_B856)
Comments Group: Clinical grade pluripotent cell line.
From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-11-0129.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC14-01.
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Gly (c.817C>G); ClinVar=VCV000634682; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): ESI BIO

Markers:
AmelogeninX
CSF1PO12
D3S135815,16
D5S81811,12
D7S82011
D8S117913
D13S31711,12
D16S53912
D18S5114,17
D21S1128
FGA21,23
Penta D9,12
Penta E11,14
TH017,8
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Web pages Provider; ESI BIO; ES-701; https://web.archive.org/web/20141201204321/http://www.esibio.com/esi-035-human-embryonic-stem-cell-line-46-xx/
Publications

PubMed=18371388; DOI=10.1016/j.stem.2007.10.004
Jeremy Micah Crook, Teija Tuulikki Peura, Lucy Kravets, Alexis Gina Bosman, Jeremy James Buzzard, Rachel Horne, Hannes Hentze, Norris Ray Dunn, Robert Zweigerdt, Florence Chua, Alan Upshall, Alan Colman;
The generation of six clinical-grade human embryonic stem cell lines.
Cell Stem Cell 1:490-494(2007)

PubMed=20177998; DOI=10.1007/s11626-010-9287-1
Shirani Sivarajah, Grace Selva Raj, Adam Joshua Varughese Mathews, Norliza Binte Esmail Sahib, Wei-Sek Hwang, Jeremy Micah Crook;
The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research.
In Vitro Cell. Dev. Biol. Anim. 46:210-216(2010)

PubMed=22265736; DOI=10.1016/j.scr.2011.10.001
Walter D. Funk, Ivan Labat, Janani Sampathkumar, Pierre-Antoine Gourraud, Jorge R. Oksenberg, Elen S. Rosler, Daniel Steiger, Nadia Sheibani, Stacy Caillier, Birgit Stache-Crain, Julie A. Johnson ...Show all 18 authors... , Lorraine Faxon Meisner, Markus D. Lacher, Karen B. Chapman, Myung Jin Park, Kyoung-Jin Shin, Radoje Drmanac, Michael D. West; Show fewer authors
Evaluating the genomic and sequence integrity of human ES cell lines comparison to normal genomes.
Stem Cell Res. 8:154-164(2012)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources hPSCreg; SSCCe007-A
NIHhESC; NIHhESC-11-0129
SKIP; SKIP002091
Encyclopedic resources Wikidata; Q54832758
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number22