Cellosaurus cell line Abcam K-562 EP300 KO (CVCL

Cross-references
Cell line name	Abcam K-562 EP300 KO
Synonyms	Human EP300 knockout K562
Accession	CVCL_B7VR
Resource Identification Initiative	To cite this cell line use: Abcam K-562 EP300 KO (RRID:CVCL_B7VR)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:3373; EP300. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110) Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0004 (K-562)
Sex of cell	Female
Age at sampling	53Y
Category	Cancer cell line
Cell line collections (Providers)	Abcam; ab277897
Encyclopedic resources	Wikidata; Q112928359
Entry history
Entry creation	23-Jun-2022
Last entry update	19-Dec-2024
Version number	7