Cellosaurus cell line e-mHepA (CVCL

Cellosaurus e-mHepA (CVCL_B7UT)

Cross-references
Cell line name	e-mHepA
Accession	CVCL_B7UT
Resource Identification Initiative	To cite this cell line use: e-mHepA (RRID:CVCL_B7UT)
Comments	Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6348; KLF4. Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Hepatocyte; CL=CL_0000182.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Category	Transformed cell line
Publications	PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645 Christoph Lipps, Franziska Klein, Tom Wahlicht, Virginia Seiffert, Milada Butueva, Jeannette Zauers, Theresa Truschel, Martin Luckner, Mario Koster, Roderick A.F. MacLeod, Jorn Pezoldt ...Show all 32 authors... , Jochen Huhn, Qing-Gong Yuan, Peter Paul Muller, Henning Kempf, Robert Zweigerdt, Oliver Dittrich-Breiholz, Thomas Pufe, Rainer Beckmann, Wolf Drescher, Jose Antonio Riancho, Carolina Sanudo, Thomas Korff, Bertram Opalka, Vera Rebmann, Joachim R. Gothert, Paula Marques Alves, Michael Ott, Roland Schucht, Hansjorg Hauser, Dagmar Wirth, Tobias May; Show fewer authors Expansion of functional personalized cells with specific transgene combinations. Nat. Commun. 9:994.1-994.12(2018)
Encyclopedic resources	Wikidata; Q112929518
Entry history
Entry creation	23-Jun-2022
Last entry update	14-Aug-2025
Version number	8