Cellosaurus logo
expasy logo

Cellosaurus e-hMEC-1 (CVCL_B7U6)

[Text version]
Cell line name e-hMEC-1
Accession CVCL_B7U6
Resource Identification Initiative To cite this cell line use: e-hMEC-1 (RRID:CVCL_B7U6)
Comments Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3527; EZH2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3796; FOS.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4317; GLI1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5109; HOXA9.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11195; SOX2.
Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin, microvascular endothelium; UBERON=UBERON_0002097+UBERON_0008339.
Cell type: Microvascular endothelial cell; CL=CL_2000008.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B7U7 ! e-hMEC-2
CVCL_B7U8 ! e-hMEC-3
Category Transformed cell line
Publications

PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645
Christoph Lipps, Franziska Klein, Tom Wahlicht, Virginia Seiffert, Milada Butueva, Jeannette Zauers, Theresa Truschel, Martin Luckner, Mario Koster, Roderick A.F. MacLeod, Jorn Pezoldt ...Show all 32 authors... , Jochen Huhn, Qing-Gong Yuan, Peter Paul Muller, Henning Kempf, Robert Zweigerdt, Oliver Dittrich-Breiholz, Thomas Pufe, Rainer Beckmann, Wolf Drescher, Jose Antonio Riancho, Carolina Sanudo, Thomas Korff, Bertram Opalka, Vera Rebmann, Joachim R. Gothert, Paula Marques Alves, Michael Ott, Roland Schucht, Hansjorg Hauser, Dagmar Wirth, Tobias May; Show fewer authors
Expansion of functional personalized cells with specific transgene combinations.
Nat. Commun. 9:994.1-994.12(2018)

Cross-references
Encyclopedic resources Wikidata; Q112929481
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number8