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Cellosaurus e-hLEC-2 (CVCL_B7U5)

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Cell line name e-hLEC-2
Accession CVCL_B7U5
Resource Identification Initiative To cite this cell line use: e-hLEC-2 (RRID:CVCL_B7U5)
Comments Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Endothelial cell of lymphatic vessel; CL=CL_0002138.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B7U4 ! e-hLEC-1
Category Transformed cell line
Publications

PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645
Christoph Lipps, Franziska Klein, Tom Wahlicht, Virginia Seiffert, Milada Butueva, Jeannette Zauers, Theresa Truschel, Martin Luckner, Mario Koster, Roderick A.F. MacLeod, Jorn Pezoldt ...Show all 32 authors... , Jochen Huhn, Qing-Gong Yuan, Peter Paul Muller, Henning Kempf, Robert Zweigerdt, Oliver Dittrich-Breiholz, Thomas Pufe, Rainer Beckmann, Wolf Drescher, Jose Antonio Riancho, Carolina Sanudo, Thomas Korff, Bertram Opalka, Vera Rebmann, Joachim R. Gothert, Paula Marques Alves, Michael Ott, Roland Schucht, Hansjorg Hauser, Dagmar Wirth, Tobias May; Show fewer authors
Expansion of functional personalized cells with specific transgene combinations.
Nat. Commun. 9:994.1-994.12(2018)

Cross-references
Encyclopedic resources Wikidata; Q112929479
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number7