Cellosaurus cell line J558L-CD40L (CVCL

Cross-references
Cell line name	J558L-CD40L
Synonyms	CD40L-J558L
Accession	CVCL_B7TP
Resource Identification Initiative	To cite this cell line use: J558L-CD40L (RRID:CVCL_B7TP)
Comments	Genetic integration: Method=Transfection; Gene=MGI; MGI:88337; Cd40lg. Genetic integration: Method=Transfection; Gene=UniProtKB; P06988; Escherichia coli hisD. Cell type: Plasma cell; CL=CL_0000786.
Disease	Mouse multiple myeloma (NCIt: C125417)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: BALB/c.
Hierarchy	Parent: CVCL_3949 (J558L)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=7615009; DOI=10.1002/eji.1830250646 Peter Lane, Corinne Burdet, Fiona McConnell, Antonio Lanzavecchia, Elisabetta Padovan; CD40 ligand-independent B cell activation revealed by CD40 ligand-deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation. Eur. J. Immunol. 25:1788-1793(1995) PubMed=8760829; DOI=10.1084/jem.184.2.747; PMCID=PMC2192696 Marina Cella, Doris Scheidegger, Kathrin Palmer-Lehmann, Peter Lane, Antonio Lanzavecchia, Gottfried Alber; Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184:747-752(1996)
Encyclopedic resources	Wikidata; Q112929891
Entry history
Entry creation	23-Jun-2022
Last entry update	14-Aug-2025
Version number	8