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Cellosaurus RIL-175-KC (CVCL_B7TM)

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Cell line name RIL-175-KC
Accession CVCL_B7TM
Resource Identification Initiative To cite this cell line use: RIL-175-KC (RRID:CVCL_B7TM)
Comments Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=MGI; MGI:108068; Cxcl1.
Caution: We are not certain that the Cxcl1 gene is from mouse or from human as the paper does not mention the source of the construct.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_B7TK (RIL-175)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Cancer cell line
Publications

PubMed=23796475; DOI=10.1016/j.jhep.2013.06.010; PMCID=PMC3805787
Tamar Kapanadze, Jaba Gamrekelashvili, Chi Ma, Carmen Chan, Fei Zhao, Stephen M. Hewitt, Lars Zender, Veena Kapoor, Dean W. Felsher, Michael Peter Manns, Firouzeh Korangy, Tim F. Greten;
Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma.
J. Hepatol. 59:1007-1013(2013)

Cross-references
Encyclopedic resources Wikidata; Q114312788
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number7