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Cellosaurus Scid.adh (CVCL_B7SC)

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Cell line name Scid.adh
Synonyms SCID.adh
Accession CVCL_B7SC
Resource Identification Initiative To cite this cell line use: Scid.adh (RRID:CVCL_B7SC)
Comments Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; MGI; MGI:104779; Prkdc; Simple; p.Tyr4046Ter (c.12138T>A) (Prkdc(scid)); Zygosity=Homozygous (from inference of genetic background of Scid mice).
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C.B.-17-scid (CB17/Icr-Prkdcscid/IcrIcoCrl).
Hierarchy Children:
CVCL_B7SF (Scid.adh.14B2)CVCL_B7SD (Scid.adh.2C2)CVCL_B7SE (Scid.adh.6D4)
Category Cancer cell line
Publications

PubMed=10452996; DOI=10.4049/jimmunol.163.5.2576
Michael Carleton, Norman R. Ruetsch, Marc A. Berger, Michele Rhodes, Steven Kaptik, David L. Wiest;
Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro.
J. Immunol. 163:2576-2585(1999)

PubMed=15882585; DOI=10.1016/j.ydbio.2005.01.027
Christopher J. Dionne, Kevin Y. Tse, Angela H. Weiss, Christopher B. Franco, David L. Wiest, Michele K. Anderson, Ellen V. Rothenberg;
Subversion of T lineage commitment by PU.1 in a clonal cell line system.
Dev. Biol. 280:448-466(2005)

Cross-references
Cell line collections (Providers) ABM; T8203
Cell line databases/resources Lonza; 69
Encyclopedic resources Wikidata; Q114312960
Entry history
Entry creation23-Jun-2022
Last entry update02-May-2024
Version number5