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Cellosaurus K-3501 (CVCL_B7RN)

[Text version]
Cell line name K-3501
Accession CVCL_B7RN
Resource Identification Initiative To cite this cell line use: K-3501 (RRID:CVCL_B7RN)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4932; HLA-B (Note=Allele B*35:01).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Proteomics; HLA class I peptidome.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=18802091; DOI=10.4049/jimmunol.181.7.4874
Hernando Escobar, David K. Crockett, Eduardo Reyes-Vargas, Andres Baena, Alan L. Rockwood, Peter E. Jensen, Julio C. Delgado;
Large scale mass spectrometric profiling of peptides eluted from HLA molecules reveals N-terminal-extended peptide motifs.
J. Immunol. 181:4874-4882(2008)

Cross-references
Encyclopedic resources Wikidata; Q112929921
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number9