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Cellosaurus MC-BR-BTY-0006 (CVCL_B7JZ)

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Cell line name MC-BR-BTY-0006
Accession CVCL_B7JZ
Resource Identification Initiative To cite this cell line use: MC-BR-BTY-0006 (RRID:CVCL_B7JZ)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Characteristics: Established from a nude mouse xenograft (PubMed=34145270).
Doubling time: 48-72 hours (PubMed=34145270).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Gln2829Leu (c.8486A>C); Zygosity=Homozygous (PubMed=34145270).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg174His (c.521G>A); Zygosity=Homozygous (PubMed=34145270).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=34145270

Markers:
AmelogeninX
CSF1PO12
D3S135815
D5S81814
D7S8209,15
D8S117911,13
D13S31711
D16S53911
D18S5116
D21S1130,31
FGA22
Penta D13,15
Penta E12
TH017
TPOX9
vWA17

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Publications

PubMed=34145270; DOI=10.1038/s41523-021-00285-x; PMCID=PMC8213738
Yong-Xian Zhuang, Jordan M. Grainger, Peter T. Vedell, Jia Yu, Ann M. Moyer, Huan-Yao Gao, Xiao-Yang Fan, Si-Si Qin, Duan Liu, Krishna R. Kalari, Matthew P. Goetz ...Show all 14 authors... , Judy C. Boughey, Richard M. Weinshilboum, Lie-Wei Wang; Show fewer authors
Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX).
NPJ Breast Cancer 7:79.1-79.12(2021)

Cross-references
Cell line collections (Providers) ABM; T8339
Encyclopedic resources Wikidata; Q112930074
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number8