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Cellosaurus HindIIIG-1 (CVCL_B7J1)

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Cell line name HindIIIG-1
Accession CVCL_B7J1
Resource Identification Initiative To cite this cell line use: HindIIIG-1 (RRID:CVCL_B7J1)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Human adenovirus C serotype 5 E1A protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03246; Human adenovirus C serotype 5 E1B 19 kDa protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A/E1B).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=24626185; DOI=10.4161/cc.28402; PMCID=PMC4050140
Zhanna V. Chitikova, Serguei A. Gordeev, Tatiana V. Bykova, Svetlana Gennadievna Zubova, Valery A. Pospelov, Tatiana V. Pospelova;
Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers.
Cell Cycle 13:1424-1439(2014)

DOI=10.1134/S1990519X2104009X
Zhanna V. Chitikova, Natalya M. Yartseva, Tatiana V. Bykova, Svetlana Gennadievna Zubova, Elena Y. Kochetkova, Valery A. Pospelov, Tatiana V. Pospelova;
Establishment of HindIIIG-1 cell line, obtained after irradiation of HindIIIG cells resistant to apoptosis, characterizes by genomic instability, altered DNA repair mechanisms and activation of autophagy.
Cell Tissue Biol. 15:370-380(2021)

Cross-references
Encyclopedic resources Wikidata; Q112929729
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number7