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Cellosaurus PC-B-148CA (CVCL_B7I2)

[Text version]
Cell line name PC-B-148CA
Accession CVCL_B7I2
Resource Identification Initiative To cite this cell line use: PC-B-148CA (RRID:CVCL_B7I2)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Southeast Asian; Thai.
Doubling time: 155.7 +- 5.2 hours (PubMed=34651665).
Karyotypic information: 47-58 chromosomes with loss of both copies of chr X (PubMed=34651665).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Mutation; HGNC; 1101; BRCA2; Simple; p.Thr3033Asnfs*11 (c.9097dupA); ClinVar=VCV000038208; Zygosity=Heterozygous (PubMed=34651665).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000040468; Zygosity=Heterozygous (PubMed=34651665).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (PubMed=34651665).
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): PubMed=34651665

Markers:
CSF1PO13
D2S133820
D3S135816,17
D5S81812,13
D7S8208,11
D8S117914,17
D13S3178
D16S53911
D18S5111,12
D19S43313.2,14.2
D21S1129,31
FGA18
TH016,9
TPOX9,12
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=34651665; DOI=10.3892/or.2021.8205
Thongchot S., Jamjuntra P., Prasopsiri J., Thuwajit P., Sawasdee N., Poungvarin N., Warnnissorn M., Sa-nguanraksa D., O-Charoenrat P., Yenchitsomanus P.-T., Thuwajit C.
Establishment and characterization of novel highly aggressive HER2-positive and triple-negative breast cancer cell lines.
Oncol. Rep. 46:254.1-254.13(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7I2
Encyclopedic resources Wikidata; Q112930253
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5