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Cellosaurus HIHCNi006-A-2 (CVCL_B7BS)

[Text version]
Cell line name HIHCNi006-A-2
Synonyms HIHCNi006-C; iPSC-SPAST_homKO
Accession CVCL_B7BS
Resource Identification Initiative To cite this cell line use: HIHCNi006-A-2 (RRID:CVCL_B7BS)
Comments From: Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, University of Tubingen; Tubingen; Germany.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11233; SPAST.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Spastic paraplegia 4 (NCIt: C129981)
Autosomal dominant spastic paraplegia type 4 (ORDO: Orphanet_100985)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B7BQ (HIHCNi006-A)
Sex of cell Male
Age at sampling 47Y
Category Induced pluripotent stem cell

PubMed=35248878; DOI=10.1016/j.scr.2022.102741
Korneck M., Wiora L., Schols L., Hauser S.
Generation of two SPAST knockout human induced pluripotent stem cell lines to create a model for hereditary spastic paraplegia type 4.
Stem Cell Res. 60:102741-102741(2022)

Cell line databases/resources hPSCreg; HIHCNi006-A-2
Encyclopedic resources Wikidata; Q112929728
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number6