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Cellosaurus RT112-CP (CVCL_B7BP)

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Cell line name RT112-CP
Accession CVCL_B7BP
Resource Identification Initiative To cite this cell line use: RT112-CP (RRID:CVCL_B7BP)
Comments Population: Caucasian.
Doubling time: 21.5 +- 1.5 hours (PubMed=2144165).
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Gene fusion; HGNC; HGNC:3690; FGFR3 + HGNC; HGNC:11524; TACC3; Name(s)=FGFR3-TACC3 (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser183Ter (c.548C>G); ClinVar=VCV000634701; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1670 (RT-112)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2144165; DOI=10.1016/0277-5379(90)90133-e
M. Claire Walker, Susan Povey, Jennifer M. Parrington, Peter N. Riddle, Ruth Knuechel, John R.W. Masters;
Development and characterization of cisplatin-resistant human testicular and bladder tumour cell lines.
Eur. J. Cancer 26:742-747(1990)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7BP
Encyclopedic resources Wikidata; Q114312927
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6