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Cellosaurus HOMC-D4 (CVCL_B7AZ)

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Cell line name HOMC-D4
Accession CVCL_B7AZ
Resource Identification Initiative To cite this cell line use: HOMC-D4 (RRID:CVCL_B7AZ)
Comments Population: Japanese.
Karyotypic information: 45,XY,-13,-22,+mar [55%] (PubMed=34663305).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Greater omentum mesothelium; UBERON=UBERON_0005670.
Cell type: Mesothelial cell; CL=CL_0000077.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B7AX ! HOMC-A4
CVCL_B7AY ! HOMC-B1
Sex of cell Male
Age at sampling 51Y
Category Transformed cell line
STR profile Source(s): PubMed=34663305

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135816,18
D5S81810,11
D7S82011,12
D8S117913,15
D13S31712
D16S5399,12
D18S5113,16
D21S1129,30
FGA21,22
Penta D10
Penta E12,19
TH016,9
TPOX8,9
vWA14

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Publications

PubMed=34663305; DOI=10.1186/s12935-021-02248-5; PMCID=PMC8525006
Tatsuhiro Sato, Hayao Nakanishi, Ken Akao, Maho Okuda, Satomi Mukai, Tohru Kiyono, Yoshitaka Sekido;
Three newly established immortalized mesothelial cell lines exhibit morphological phenotypes corresponding to malignant mesothelioma epithelioid, intermediate, and sarcomatoid types, respectively.
Cancer Cell Int. 21:546.1-546.11(2021)

Cross-references
Encyclopedic resources Wikidata; Q111733446
Gene expression databases GEO; GSM3684946
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number9