Cellosaurus cell line ZX2021H (CVCL

Cellosaurus ZX2021H (CVCL_B6ZD)

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Cell line name

ZX2021H

Synonyms

TJYK-ZLL-01

Accession

CVCL_B6ZD

Resource Identification Initiative

To cite this cell line use: ZX2021H (RRID:CVCL_B6ZD)

Comments

Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2021215.
Population: Chinese.
Doubling time: ~29.8 hours (PubMed=35297208).
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Asp22Asn (c.64G>A); ClinVar=VCV000040335; Zygosity=Unspecified (PubMed=35297208).
Mutation; HGNC; HGNC:7765; NF1; Simple; p.Cys2134Tyrfs*8 (c.6401_6402delGT) (p.L2133fs, c.6398_6399del); ClinVar=VCV000818199; Zygosity=Unspecified (PubMed=35297208).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Arg (c.536A>G); ClinVar=VCV000376606; Zygosity=Unspecified (PubMed=35297208).

Disease

Lung adenocarcinoma (NCIt: C3512)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

42Y

Category

Cancer cell line

STR profile

Source(s): Patent=CN113817684B; PubMed=35297208

Markers:

Amelogenin	X
CSF1PO	12
D2S441	10
D2S1338	19
D3S1358	16
D5S818	9
D6S1043	14
D7S820	8,12
D8S1179	13
D12S391	20
D13S317	9,11
D16S539	9,12
D18S51	14,16
D19S433	13,15.2
D21S11	31
FGA	19,21
Penta D	12
Penta E	13
TH01	7,9
TPOX	8
vWA	17

Publications

PubMed=35297208; DOI=10.1111/1759-7714.14385; PMCID=PMC9013652
Ling-Ling Zu, Xue-Bing Li, Jin-Ling He, Ning Zhou, Fan-Rong Meng, Xiao-Zhou Li, Song Xu, Lei Zhang;
Establishment and characterization of a novel highly malignant lung cancer cell line ZX2021H derived from a metastatic lymph node lesion.
Thorac. Cancer 13:1199-1210(2022)

Patent=CN113817684B
Song Xu, Ling-Ling Zu, Jin-Ling He, Shuai Zhu, Ning Zhou, Xin Jin, Ling-Qi Yang, Yi-Fan Zhu, Xi Lei;
Chinese lung adenocarcinoma cell line with high lymph node metastasis potential and application thereof.
Patent number CN113817684B, 19-Sep-2023

Cross-references

Cell line databases/resources

cancercelllines; CVCL_B6ZD
CCRID; 4201PAT-CCTCC01828

Encyclopedic resources

Wikidata; Q112041948

Entry history

Entry creation

17-Mar-2022

Last entry update

10-Apr-2025

Version number