Cellosaurus cell line ACRJ-PC28 (CVCL

Cellosaurus ACRJ-PC28 (CVCL_B6XF)

Cross-references
Cell line name	ACRJ-PC28
Synonyms	Anti Cancer Research Jamaica-Prostate Cancer 28
Accession	CVCL_B6XF
Resource Identification Initiative	To cite this cell line use: ACRJ-PC28 (RRID:CVCL_B6XF)
Comments	Population: Caribbean; Jamaican. Characteristics: Lack of expression of AR (DOI=10.1158/1538-7755.DISP21-PO-138; PubMed=36643868). Doubling time: 45 hours (DOI=10.1158/1538-7755.DISP21-PO-138; PubMed=36643868). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1787; CDKN2A. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Omics: Transcriptomics; RNAseq. Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease	Prostate carcinoma (NCIt: C4863)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	69Y
Category	Cancer cell line
Web pages	Info; -; -; https://www.cancer.gov/about-nci/organization/cgh/blog/2021/grantee-spotlight-badal
Publications	DOI=10.1158/1538-7755.DISP21-PO-138 Henkel Valentine, William Aiken, Belinda Morrison, Zi-Ran Zhao, Holly Fowle, Jason S. Wasserman, Elon Thompson, Warren Chin, Mark Young, Shannique Clarke, Denise Gibbs ...Show all 23 authors... , Sharon Harrison, Wayne McLaughlin, Tim Kwok, Fang Jin, Kerry S. Campbell, Anelia Horvath, Rory Thompson, Norman H. Lee, Yan Zhou, Xavier Grana, Camille C.R. Ragin, Simone Anne Marie Badal-McCreath; Show fewer authors The first Caribbean cell line, a prostate cancer cell line: ACRJ-PC28. Cancer Epidemiol. Biomarkers Prev. 31 Suppl. 1:PO138-PO138(2022) PubMed=36643868; DOI=10.1158/2767-9764.CRC-22-0245; PMCID=PMC9836004 Henkel Valentine, William Aiken, Belinda Morrison, Zi-Ran Zhao, Holly Fowle, Jason S. Wasserman, Elon Thompson, Warren Chin, Mark Young, Shannique Clarke, Denise Gibbs ...Show all 23 authors... , Sharon Harrison, Wayne McLaughlin, Tim Kwok, Fang Jin, Kerry S. Campbell, Anelia Horvath, Rory Thompson, Norman H. Lee, Yan Zhou, Xavier Grana, Camille C.R. Ragin, Simone Anne Marie Badal-McCreath; Show fewer authors Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient. Cancer Res. Commun. 2:1355-1371(2022)
Cell line collections (Providers)	ABM; T0398
Encyclopedic resources	Wikidata; Q111732869
Entry history
Entry creation	17-Mar-2022
Last entry update	10-Apr-2025
Version number	8