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Cellosaurus TU165 (CVCL_B6T0)

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Cell line name TU165
Synonyms TUE165
Accession CVCL_B6T0
Resource Identification Initiative To cite this cell line use: TU165 (RRID:CVCL_B6T0)
Comments Characteristics: Produces a mAb that acts in a T-cell receptor-like manner (PubMed=8449221).
Characteristics: The produced mAb recognizes the nonapeptide LPPHDITPY from EBV EBNA6/EBNA3C when bound to HLAB*35:01 (PubMed=9878435).
Monoclonal antibody isotype: IgM, kappa.
Monoclonal antibody target: UniProtKB; P01889; Human HLA-B (Note=Recognizes allele B*35:01).
Monoclonal antibody target: UniProtKB; P03204; Epstein-Barr virus (strain B95-8) nuclear antigen 6 (Note=Recognizes AA 98-106).
Caution: TU165 has a U umlaut and should thus be transcribed as TUE165, but the umlaut is most often ommitted in online resources.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=8449221; DOI=10.1002/eji.1830230325
Barbara Uchanska-Ziegler, Elfriede Noessner, Andrea Schenk, Andreas Ziegler, Dolores Jean Schendel;
Soluble T cell receptor-like properties of an HLA-B35-specific monoclonal antibody (TU165).
Eur. J. Immunol. 23:734-738(1993)

PubMed=9878435; DOI=10.1006/jmbi.1998.2363
Ruth Menssen, Peter Orth, Andreas Ziegler, Wolfram Saenger;
Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus.
J. Mol. Biol. 285:645-653(1999)

Cross-references
Encyclopedic resources Wikidata; Q112041870
Entry history
Entry creation17-Mar-2022
Last entry update27-Nov-2025
Version number5