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Cellosaurus 2R (CVCL_B6QX)

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Cell line name 2R
Accession CVCL_B6QX
Resource Identification Initiative To cite this cell line use: 2R (RRID:CVCL_B6QX)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=3028610
Spiridione Garbisa, Rudy Pozzatti, Ruth J. Muschel, Umberto Saffiotti, Marina Ballin, Ronald H. Goldfarb, George Khoury, Lance Allen Liotta;
Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.
Cancer Res. 47:1523-1528(1987)

PubMed=2655894
Sebastiano Gattoni-Celli, Robert M. Strauss, Christopher G. Willett, Rudy Pozzatti, Kurt Julius Isselbacher;
Modulation of the transformed and neoplastic phenotype of rat fibroblasts by MHC-I gene expression.
Cancer Res. 49:3392-3395(1989)

Cross-references
Encyclopedic resources Wikidata; Q111732705
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number7