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Cellosaurus 2R (CVCL_B6QX)

[Text version]
Cell line name 2R
Accession CVCL_B6QX
Resource Identification Initiative To cite this cell line use: 2R (RRID:CVCL_B6QX)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=3028610
Garbisa S., Pozzatti R., Muschel R.J., Saffiotti U., Ballin M., Goldfarb R.H., Khoury G., Liotta L.A.
Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.
Cancer Res. 47:1523-1528(1987)

PubMed=2655894
Gattoni-Celli S., Strauss R.M., Willett C.G., Pozzatti R., Isselbacher K.J.
Modulation of the transformed and neoplastic phenotype of rat fibroblasts by MHC-I gene expression.
Cancer Res. 49:3392-3395(1989)

Cross-references
Encyclopedic resources Wikidata; Q111732705
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number6