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Cellosaurus TJU-UM001 (CVCL_B6PW)

[Text version]
Cell line name TJU-UM001
Synonyms UM001; Thomas Jefferson University-Uveal Melanoma 001
Accession CVCL_B6PW
Resource Identification Initiative To cite this cell line use: TJU-UM001 (RRID:CVCL_B6PW)
Comments Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B6PZ (TJU-UM001-tdTomato)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=24354797; DOI=10.1111/pcmr.12206
Makoto Yoshida, Senthamil R. Selvan, Peter A. McCue, Tiziana DeAngelis, Renato Baserga, Ami Fujii, Hallgeir Rui, Michael Joseph Mastrangelo, Takami Sato;
Expression of insulin-like growth factor-1 receptor in metastatic uveal melanoma and implications for potential autocrine and paracrine tumor cell growth.
Pigment Cell Melanoma Res. 27:297-308(2014)

PubMed=25952648; DOI=10.1158/0008-5472.CAN-15-0370; PMCID=PMC4490069
Han-Yin Cheng, Mizue Terai, Ken Kageyama, Shinji Ozaki, Peter A. McCue, Takami Sato, Andrew E. Aplin;
Paracrine effect of NRG1 and HGF drives resistance to MEK inhibitors in metastatic uveal melanoma.
Cancer Res. 75:2737-2748(2015)

PubMed=26613897; DOI=10.1016/j.ajpath.2015.09.011; PMCID=PMC4715216
Shinji Ozaki, Raja Vuyyuru, Ken Kageyama, Mizue Terai, Masahiro Ohara, Han-Yin Cheng, Timothy L. Manser, Michael Joseph Mastrangelo, Andrew E. Aplin, Takami Sato;
Establishment and characterization of orthotopic mouse models for human uveal melanoma hepatic colonization.
Am. J. Pathol. 186:43-56(2016)

PubMed=32430489; DOI=10.1158/1535-7163.MCT-19-1016; PMCID=PMC7415561
Jessica L.F. Teh, Timothy J. Purwin, Anna Han, Vivian Chua, Prem Patel, Usman Baqai, Connie Liao, Nelisa Bechtel, Takami Sato, Michael A. Davies, Julio A. Aguirre-Ghiso, Andrew E. Aplin;
Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma.
Mol. Cancer Ther. 19:1719-1726(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6PW
Encyclopedic resources Wikidata; Q112041791
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number7