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Cellosaurus U2OS CHMP2B KO (CVCL_B6JX)

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Cell line name U2OS CHMP2B KO
Accession CVCL_B6JX
Resource Identification Initiative To cite this cell line use: U2OS CHMP2B KO (RRID:CVCL_B6JX)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:24537; CHMP2B.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=37635943; DOI=10.12688/f1000research.139755.1; PMCID=PMC10448144
Walaa Alshafie, Maryam Fotouhi, Riham Ayoubi, Irina Shlaifer, Kathleen Southern, Peter Scott McPherson, Carl Laflamme;
NeuroSGC/YCharOS/EDDU Collaborative Group
The identification of high-performing antibodies for charged multivesicular body protein 2b for use in western blot, immunoprecipitation and immunofluorescence.
F1000Research 12:884.1-884.13(2023)

Cross-references
Encyclopedic resources Wikidata; Q112041874
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7