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Cellosaurus Mel Ibr (CVCL_B6JK)

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Cell line name Mel Ibr
Synonyms mel Ibr; Mel IBR
Accession CVCL_B6JK
Resource Identification Initiative To cite this cell line use: Mel Ibr (RRID:CVCL_B6JK)
Comments Group: Patented cell line.
Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 689D.
Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=28881731).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B6KC (Mel Ibr subclone)CVCL_B6L2 (Mel IG)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=16107020
Irina Nikolaevna Mikhailova, Marina Igorevna Lukashina, Anatoly Yurievich Baryshnikov, Lidia Fyodorovna Morozova, Olga Semyonovna Burova, Tatiana Nikolaevna Palkina, Alexey Mikhailovich Kozlov, Valentina A. Golubeva, Eugene A. Cheremushkin, Maria B. Doroshenko, Lev Vadimovich Demidov ...Show all 14 authors... , Sergey L'vovich Kiselev, Sergey Sergeevich Larin, Georgii Pavlovich Georgiev; Show fewer authors
Melanoma cell lines as the basis for antitumor vaccine preparation.
Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005)

CLPUB00681
Alexey Evgenyevich Berezhnoy, Irina R. Zakeyeva, Alexey Vladimirovich Kibardin, A.D. Chernysheva, Vladimir Mikhailovich Moiseyenko, Alexey Olegovich Danilov, Lev Vadimovich Demidov, Anatoly Yurievich Baryshnikov, Nikolay Vasilyevich Gnuchev, Georgii Pavlovich Georgiev, Sergey Sergeevich Larin;
Analysis of HLA-E expression in human melanoma cells.
Ross. Bioterap. Zh. 5:66-71(2006)

Patent=RU2287576
Irina Nikolaevna Mikhailova, Anatoly Yurievich Baryshnikov, Lidia Fyodorovna Morozova, Alexey Evgenyevich Berezhnoy, Alexey Mikhailovich Kozlov, Sergey Sergeevich Larin, Georgii Pavlovich Georgiev, Georgy Nikolaevich Vorozhtsov, Nikolay Vasilyevich Gnuchev;
Human melanoma cellular line mel Ibr used in preparing antitumor vaccine.
Patent number RU2287576, 20-Nov-2006

PubMed=18781128; DOI=10.1097/CMR.0b013e32830e391d
Irina Nikolaevna Mikhailova, Dmitry A. Kovalevsky, Lidia Fyodorovna Morozova, Valentina A. Golubeva, Eugene A. Cheremushkin, Marina Igorevna Lukashina, Ekaterina Sergeevna Voronina, Olga Semyonovna Burova, Igor A. Utyashev, Sergey L'vovich Kiselev, Lev Vadimovich Demidov ...Show all 13 authors... , Robert S. Beabealashvilli, Anatoly Yurievich Baryshnikov; Show fewer authors
Cancer/testis genes expression in human melanoma cell lines.
Melanoma Res. 18:303-313(2008)

PubMed=26388567; DOI=10.1007/s10517-015-3007-5
Natal'ya M. Suraeva, Lidia Fyodorovna Morozova, Artem Vladimirovich Samoylov, Olga Semyonovna Burova, Valentina A. Golubeva, Maria Anatolyevna Baryshnikova, Anatoly Yurievich Baryshnikov;
Changes in the morphological and immunological characteristics of Mel Ibr melanoma cells in response to chicken embryo extract.
Bull. Exp. Biol. Med. 159:520-523(2015)

CLPUB00680
Irina Nikolaevna Mikhailova, Anatoly Yurievich Baryshnikov, Lidia Fyodorovna Morozova, Olga Semyonovna Burova, Irina Zhanovna Shubina, Dmitry A. Kovalevsky, Ekaterina Sergeevna Voronina, Helena Mikhailovna Treshalina, Anna A. Lushnikova, Irina V. Tsyganova, Natalia N. Mazurenko;
Human skin melanoma cell lines collection.
(In book chapter) Management of malignant melanoma; No_last_name, No_first_name (eds.); pp.6.1-6.6; SM Group; Dover; USA (2016)

PubMed=28726209; DOI=10.1007/s10517-017-3778-y
Natal'ya M. Suraeva, Lidia Fyodorovna Morozova, Oksana O. Ryabaya, Y.A. Khochenkova, Artem Vladimirovich Samoylov, Olga Semyonovna Burova, Natalya Valerievna Golubtsova, Alexander E. Barmashov, Maria Anatolyevna Baryshnikova;
Characteristics of Mel Ibr melanoma line subclone after treatment with chicken embryo extract.
Bull. Exp. Biol. Med. 163:255-259(2017)

PubMed=28881731; DOI=10.18632/oncotarget.17014; PMCID=PMC5581030
Marina Emelyanova, Lilit Ghukasyan, Ivan Abramov, Oxana Ryabaya, Evgenia Vladislavovna Stepanova, Anna Viktorovna Kudryavtseva, Asiya Sadritdinova, Cholpon Dzhumakova, Tatiana Belysheva, Sergey Surzhikov, Lyudmila Lyubchenko ...Show all 13 authors... , Alexander Zasedatelev, Tatiana Nasedkina; Show fewer authors
Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.
Oncotarget 8:52304-52320(2017)

DOI=10.17650/1726-9784-2018-17-4-27-35
Irina Nikolaevna Mikhailova, Helena Mikhailovna Treshalina, Lidia Fyodorovna Morozova, Nataliya V. Andronova, Irina Zhanovna Shubina, Anna A. Lushnikova;
Cell lines of human melanoma and their xenograft with BRAF or NRAS mutations a targets for targeted therapy.
Ross. Bioterap. Zh. 17:27-35(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6JK
Encyclopedic resources Wikidata; Q112129270
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number7