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Cellosaurus mEERL95 (CVCL_B6JB)

[Text version]
Cell line name mEERL95
Accession CVCL_B6JB
Resource Identification Initiative To cite this cell line use: mEERL95 (RRID:CVCL_B6JB)
Comments Characteristics: Established from a tumor in a C57BL/6JRj mouse which was implanted with the parent cell line (PubMed=29313973).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Pharynx, oropharynx; UBERON=UBERON_0001729.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_B6J3 (mEERL)
Sex of cell Male
Age at sampling 6-8W
Category Transformed cell line
Publications

PubMed=29313973; DOI=10.1002/ijc.31240
Maxime Mermod, Agnes Hiou-Feige, Esther Bovay, Vincent Roh, Jana Sponarova, Massimo Bongiovanni, Daniel W. Vermeer, John H. Lee, Tatiana V. Petrova, Jean-Paul Rivals, Yan Monnier ...Show all 13 authors... , Genrich V. Tolstonog, Christian Simon; Show fewer authors
Mouse model of postsurgical primary tumor recurrence and regional lymph node metastasis progression in HPV-related head and neck cancer.
Int. J. Cancer 142:2518-2528(2018)

Cross-references
Encyclopedic resources Wikidata; Q112129253
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number9