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Cellosaurus WB6 (CVCL_B6FB)

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Cell line name WB6
Accession CVCL_B6FB
Resource Identification Initiative To cite this cell line use: WB6 (RRID:CVCL_B6FB)
Comments Characteristics: Proliferates at the permissive temperature (33 Celsius). Rapid decrease in cell proliferation at the restrictive temperature (39 Celsius) (PubMed=10762059).
Doubling time: 28.7 hours (Note=At 15th passage), 23.5 hours (Note=At 50th passage) (PubMed=10762059).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.
Sex of cell Sex unspecified
Age at sampling Adult
Category Conditionally immortalized cell line
Publications

PubMed=10762059; DOI=10.1038/emm.2000.6
Byung-Ho Kim, Se-Ra Sung, Eun-Hee Choi, Young-Il Kim, Kyeong-Jin Kim, Seok-Ho Dong, Hyo-Jong Kim, Young-Woon Chang, Joung-Il Lee, Rin Chang;
Dedifferentiation of conditionally immortalized hepatocytes with long-term in vitro passage.
Exp. Mol. Med. 32:29-37(2000)

Cross-references
Encyclopedic resources Wikidata; Q112041930
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number9