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Cellosaurus BRAD-3 (CVCL_B6E6)

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Cell line name BRAD-3
Synonyms BRAD3; 1A3-3
Accession CVCL_B6E6
Resource Identification Initiative To cite this cell line use: BRAD-3 (RRID:CVCL_B6E6)
Comments Monoclonal antibody isotype: IgG3, kappa.
Monoclonal antibody target: UniProtKB; Q02161; Human RHD.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=7655002; DOI=10.1182/blood.V86.5.1701.bloodjournal8651701
Belinda M. Kumpel, M. Jean Goodrick, Derwood Harold Pamphilon, Ian D. Fraser, Geoffrey D. Poole, Colin Morse, Graham R. Standen, George E. Chapman, Duncan P. Thomas, David John Anstee;
Human Rh D monoclonal antibodies (BRAD-3 and BRAD-5) cause accelerated clearance of Rh D+ red blood cells and suppression of Rh D immunization in Rh D- volunteers.
Blood 86:1701-1709(1995)

PubMed=11889904; DOI=10.1016/S1246-7820(01)00209-9
Belinda M. Kumpel;
In vivo studies of monoclonal anti-D and the mechanism of immune suppression.
Transfus. Clin. Biol. 9:9-14(2002)

PubMed=32001734; DOI=10.1038/s41598-019-57393-9; PMCID=PMC6992666
Belinda M. Kumpel, Radka Saldova, Carolien A.M. Koeleman, Jodie L. Abrahams, Agnes Hipgrave Ederveen, Kathryn L. Armour, Natalia I. Olovnikova, Gestur Vidarsson, Rick Kapur, Pauline Mary Rudd, Manfred Wuhrer;
Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy.
Sci. Rep. 10:1464.1-1464.14(2020)

Cross-references
Encyclopedic resources Wikidata; Q111732993
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number4