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Cellosaurus TMhep48 (CVCL_B6DQ)

[Text version]
Cell line name TMhep48
Synonyms TMHepTG3960 x 2984 x 4912 48; TMHepTG3960 x 2984 x 4912 line 48
Accession CVCL_B6DQ
Resource Identification Initiative To cite this cell line use: TMhep48 (RRID:CVCL_B6DQ)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-989.
Characteristics: Established from a triple transgenic mice that contains 1) a human SERPINA1 promoter driving the expression of a mouse Myc as well as a second SERPINA1 promoter in front of a full copy of SERPINA1, 2) a human SERPINA1 promoter driving the expression of SV40 T-antigen and 3) a human F9 promoter driving the expression of F9 (PubMed=1369183).
Transfected with: HGNC; 8941; SERPINA1.
Transfected with: HGNC; 3551; F9.
Transfected with: MGI; MGI:97250; Myc.
Transformant: Myc.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x SJL transgenic TG3960 x TG2984 x TG4912.
Category Cancer cell line
Publications

PubMed=1369183; DOI=10.1007/BF02521733
Perraud F., Dalemans W., Ali-Hadji D., Pavirani A.
Novel cell lines derived from transgenic mice expressing recombinant human proteins. Transgenic hepatoma-derived cell lines.
Cytotechnology 9:69-75(1992)

Patent=US5814716
Jallat S., Meulien P., Pavirani A., Perraud F.
Cell lines from a transgenic mouse which express biologically active IX factor.
Patent number US5814716, 29-Sep-1998

Cross-references
Encyclopedic resources Wikidata; Q112041798
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number4