Cellosaurus cell line TMHepTG4912 10 (CVCL

Cross-references
Cell line name	TMHepTG4912 10
Synonyms	TMHepTG4912 line 10; TM hep TG 4912/10
Accession	CVCL_B6DN
Resource Identification Initiative	To cite this cell line use: TMHepTG4912 10 (RRID:CVCL_B6DN)
Comments	Characteristics: Established from a transgenic mice that contains a human SERPINA1 promoter driving the expression of SV40 T-antigen (PubMed=1369183). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease	Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 x SJL transgenic TG4912.
Category	Cancer cell line
Publications	PubMed=1711473; DOI=10.1016/0014-4827(91)90500-t Frederic Perraud, Wilfried Dalemans, Jean-Louis Gendrault, Dominique Dreyer, Dalila Ali-Hadji, Theres Faure, Andrea Pavirani; Characterization of trans-immortalized hepatic cell lines established from transgenic mice. Exp. Cell Res. 195:59-65(1991) PubMed=1369183; DOI=10.1007/BF02521733 Frederic Perraud, Wilfried Dalemans, Dalila Ali-Hadji, Andrea Pavirani; Novel cell lines derived from transgenic mice expressing recombinant human proteins. Transgenic hepatoma-derived cell lines. Cytotechnology 9:69-75(1992)
Encyclopedic resources	Wikidata; Q112041800
Entry history
Entry creation	17-Mar-2022
Last entry update	14-Aug-2025
Version number	6