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Cellosaurus TMHepTG4912 10 (CVCL_B6DN)

[Text version]
Cell line name TMHepTG4912 10
Synonyms TMHepTG4912 line 10; TM hep TG 4912/10
Accession CVCL_B6DN
Resource Identification Initiative To cite this cell line use: TMHepTG4912 10 (RRID:CVCL_B6DN)
Comments Characteristics: Established from a transgenic mice that contains a human SERPINA1 promoter driving the expression of SV40 T-antigen (PubMed=1369183).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x SJL transgenic TG4912.
Category Cancer cell line
Publications

PubMed=1711473; DOI=10.1016/0014-4827(91)90500-t
Frederic Perraud, Wilfried Dalemans, Jean-Louis Gendrault, Dominique Dreyer, Dalila Ali-Hadji, Theres Faure, Andrea Pavirani;
Characterization of trans-immortalized hepatic cell lines established from transgenic mice.
Exp. Cell Res. 195:59-65(1991)

PubMed=1369183; DOI=10.1007/BF02521733
Frederic Perraud, Wilfried Dalemans, Dalila Ali-Hadji, Andrea Pavirani;
Novel cell lines derived from transgenic mice expressing recombinant human proteins. Transgenic hepatoma-derived cell lines.
Cytotechnology 9:69-75(1992)

Cross-references
Encyclopedic resources Wikidata; Q112041800
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number6