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Cellosaurus TMHepTG2984 2 (CVCL_B6DM)

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Cell line name TMHepTG2984 2
Synonyms TMHepTG2984 line 2; TM hep TG 2984/2
Accession CVCL_B6DM
Resource Identification Initiative To cite this cell line use: TMHepTG2984 2 (RRID:CVCL_B6DM)
Comments Characteristics: Established from a transgenic mice that contains a human SERPINA1 promoter driving the expression of a mouse Myc as well as a second SERPINA1 promoter in front of a full copy of SERPINA1 (PubMed=1369183).
Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:8941; SERPINA1.
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:97250; Myc.
Transformant: Myc.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x SJL transgenic TG2984.
Category Cancer cell line
Publications

PubMed=1711473; DOI=10.1016/0014-4827(91)90500-t
Frederic Perraud, Wilfried Dalemans, Jean-Louis Gendrault, Dominique Dreyer, Dalila Ali-Hadji, Theres Faure, Andrea Pavirani;
Characterization of trans-immortalized hepatic cell lines established from transgenic mice.
Exp. Cell Res. 195:59-65(1991)

PubMed=1369183; DOI=10.1007/BF02521733
Frederic Perraud, Wilfried Dalemans, Dalila Ali-Hadji, Andrea Pavirani;
Novel cell lines derived from transgenic mice expressing recombinant human proteins. Transgenic hepatoma-derived cell lines.
Cytotechnology 9:69-75(1992)

Cross-references
Encyclopedic resources Wikidata; Q112041799
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number6