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Cellosaurus RG-233 (CVCL_B651)

[Text version]
Cell line name RG-233
Synonyms SI-233; SC233; RGIe133-A
Accession CVCL_B651
Resource Identification Initiative To cite this cell line use: RG-233 (RRID:CVCL_B651)
Comments From: Reproductive Genetics Institute; Chicago; USA.
Registration: NIH Human Embryonic Stem Cell Registry; not approved.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; 4827; HBB; Simple; p.Glu7Val (c.20A>T) (E6V); ClinVar=VCV000015333; Zygosity=Homozygous (PubMed=20541472).
Disease Sickle cell disease (NCIt: C34383)
Sickle cell anemia (ORDO: Orphanet_232)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://grants.nih.gov/stem_cells/registry/not_approved.htm

PubMed=20541472; DOI=10.1016/j.rbmo.2010.04.017
Pryzhkova M.V., Peters A., Zambidis E.T.
Erythropoietic differentiation of a human embryonic stem cell line harbouring the sickle cell anaemia mutation.
Reprod. BioMed. Online 21:196-205(2010)

Cell line databases/resources hPSCreg; RGIe133-A
ISCR; 448
SKIP; SKIP002232
Encyclopedic resources Wikidata; Q54950017
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number14