Cellosaurus logo
expasy logo

Cellosaurus C2BBe1 MRP5 KO (CVCL_B5ZZ)

[Text version]
Cell line name C2BBe1 MRP5 KO
Synonyms Caco-2 MRP5 Knockout Cell Line; C2BBe1 MRP5 Knockout Cell Line
Accession CVCL_B5ZZ
Resource Identification Initiative To cite this cell line use: C2BBe1 MRP5 KO (RRID:CVCL_B5ZZ)
Comments Population: Caucasian.
Knockout cell: Method=ZFN; HGNC; 56; ABCC5.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1096 (C2BBe1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Web pages https://www.sigmaaldrich.com/catalog/product/sigma/mtox1095
https://www.sigmaaldrich.com/catalog/product/sigma/mtox1095P24
Cross-references
Cell line databases/resources cancercelllines; CVCL_B5ZZ
Encyclopedic resources Wikidata; Q111733046
Entry history
Entry creation17-Mar-2022
Last entry update05-Oct-2023
Version number6