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Cellosaurus MMH-E14 (CVCL_B5WT)

[Text version]
Cell line name MMH-E14
Synonyms MMH E14; E14; Met Murine Hepatocytes-E14
Accession CVCL_B5WT
Resource Identification Initiative To cite this cell line use: MMH-E14 (RRID:CVCL_B5WT)
Comments Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:7029; MET (Note=With p.Met1_Leu955del = cyto-Met).
Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Children:
CVCL_B5WU (MMH-E14 ep.)CVCL_B5WV (MMH-E14 pal.)
Sex of cell Sex unspecified
Age at sampling 14FD
Category Spontaneously immortalized cell line
Publications

PubMed=9034332; DOI=10.1093/emboj/16.3.495; PMCID=PMC1169653
Amicone L., Spagnoli F.M., Spath G.F., Giordano S., Tommasini C., Bernardini S., De Luca V., Della Rocca C., Weiss M.C., Comoglio P.M., Tripodi M.
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes.
EMBO J. 16:495-503(1997)

PubMed=9817765; DOI=10.1083/jcb.143.4.1101; PMCID=PMC2132947
Spagnoli F.M., Amicone L., Tripodi M., Weiss M.C.
Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver.
J. Cell Biol. 143:1101-1112(1998)

PubMed=9828230; DOI=10.1002/hep.510280626
Aiuti A., Cicchini C., Bernardini S., Fedele G., Amicone L., Fantoni A., Tripodi M.
Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH).
Hepatology 28:1645-1654(1998)

Cross-references
Encyclopedic resources Wikidata; Q112129338
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number6