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Cellosaurus MMH-D6 (CVCL_B5WS)

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Cell line name MMH-D6
Synonyms MMH D6; D6; Met Murine Hepatocytes-D6
Accession CVCL_B5WS
Resource Identification Initiative To cite this cell line use: MMH-D6 (RRID:CVCL_B5WS)
Comments Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:7029; MET (Note=With p.Met1_Leu955del = cyto-Met).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Age at sampling 6D
Category Spontaneously immortalized cell line
Publications

PubMed=9034332; DOI=10.1093/emboj/16.3.495; PMCID=PMC1169653
Laura Amicone, Francesca Maria Spagnoli, Gerald Frank Spath, Silvia Giordano, Cristina Tommasini, Silvia Bernardini, Veronica De Luca, Carlo Della Rocca, Mary C. Weiss, Paolo Maria Comoglio, Marco Tripodi;
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes.
EMBO J. 16:495-503(1997)

PubMed=9828230; DOI=10.1002/hep.510280626
Alessandro Aiuti, Carla Cicchini, Silvia Bernardini, Giorgio Fedele, Laura Amicone, Antonio Fantoni, Marco Tripodi;
Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH).
Hepatology 28:1645-1654(1998)

Cross-references
Encyclopedic resources Wikidata; Q112129337
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number6