Cellosaurus cell line AG27609 (CVCL

Cross-references
Cell line name	AG27609
Synonyms	AG27609*B
Accession	CVCL_B5PR
Resource Identification Initiative	To cite this cell line use: AG27609 (RRID:CVCL_B5PR)
Comments	Population: Caucasian. Derived from site: In situ; Thigh, skin; UBERON=UBERON_0004262. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=30699343).
Disease	Alzheimer's disease (NCIt: C2866)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_4M37 (AG10788)
Sex of cell	Female
Age at sampling	87Y
Category	Induced pluripotent stem cell
Publications	PubMed=30699343; DOI=10.1016/j.celrep.2019.01.023; PMCID=PMC6386196 Katharina Meyer, Heather M. Feldman, Tao Lu, Derek Drake, Elaine Teng-Tim Lim, King-Hwa Ling, Nicholas A. Bishop, Ying Pan, Jinsoo Seo, Yuan-Ta Lin, Susan C. Su ...Show all 14 authors... , George McDonald Church, Li-Huei Tsai, Bruce A. Yankner; Show fewer authors REST and neural gene network dysregulation in iPSC models of Alzheimer's disease. Cell Rep. 26:1112-1127.e9(2019)
Cell line collections (Providers)	Coriell; AG27609
Encyclopedic resources	Wikidata; Q111732884
Entry history
Entry creation	17-Mar-2022
Last entry update	19-Dec-2024
Version number	5