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Cellosaurus KOT52 (CVCL_B5NT)

[Text version]
Cell line name KOT52
Accession CVCL_B5NT
Resource Identification Initiative To cite this cell line use: KOT52 (RRID:CVCL_B5NT)
Comments Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
Knockout cell: Method=KO mouse; MGI; MGI:102676; Abcc1.
Derived from site: In situ; Ear, skin; UBERON=UBERON_0001459.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Children:
CVCL_B5NU (KOT52/D320)CVCL_B5NV (KOT52/D80)CVCL_B5NW (KOT52/D800)
Sex of cell Sex unspecified
Category Spontaneously immortalized cell line
Publications

PubMed=10485464
John D. Allen, Remco F. Brinkhuis, Jan Wijnholds, Alfred H. Schinkel;
The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin.
Cancer Res. 59:4237-4241(1999)

PubMed=11956086
John D. Allen, Sonja C. Jackson, Alfred H. Schinkel;
A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance.
Cancer Res. 62:2294-2299(2002)

Cross-references
Encyclopedic resources Wikidata; Q111733555
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number4