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Cellosaurus 1C11 [Mouse teratocarcinoma] (CVCL_B5MU)

[Text version]
Cell line name 1C11 [Mouse teratocarcinoma]
Accession CVCL_B5MU
Resource Identification Initiative To cite this cell line use: 1C11 [Mouse teratocarcinoma] (RRID:CVCL_B5MU)
Comments Characteristics: Tumorigenic in syngeneic mice (PubMed=2155426).
Characteristics: Presents two states: an immature phenotype (1C11 precursor) and a more differentiated state (1C11*). After induction by Bt2cAMP and cyclohexanecarboxylate, 1C11* cells extend neurites and express neural markers such as NCAM1, synaptophysin and [Met5]enkephalin in >95% of the clonal population (PubMed=2155426).
Doubling time: 20 hours (PubMed=2155426).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Disease Mouse teratocarcinoma (NCIt: C129859)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129/Sv.
Hierarchy Parent: CVCL_B5MT (F9K4b2)
Sex of cell Male
Age at sampling Embryo
Category Cancer cell line

PubMed=2155426; DOI=10.1073/pnas.87.5.1922
Buc-Caron M.-H., Launay J.-M., Lamblin D., Kellermann O.
Serotonin uptake, storage, and synthesis in an immortalized committed cell line derived from mouse teratocarcinoma.
Proc. Natl. Acad. Sci. U.S.A. 87:1922-1926(1990)

Encyclopedic resources Wikidata; Q111732620
Entry history
Entry creation17-Mar-2022
Last entry update21-Mar-2023
Version number3