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Cellosaurus 1B5 [Mouse myogenic] (CVCL_B5J2)

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Cell line name 1B5 [Mouse myogenic]
Accession CVCL_B5J2
Resource Identification Initiative To cite this cell line use: 1B5 [Mouse myogenic] (RRID:CVCL_B5J2)
Comments Characteristics: Can be induced to differentiate into noncontractile multinucleated myotubes (PubMed=9472036).
Doubling time: ~18-24 hours (PubMed=9472036).
Knockout cell: Method=KO mouse; MGI; MGI:99659; Ryr1.
Genetic integration: Method=Transduction; Gene=MGI; MGI:97275; Myod1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134.
Cell type: Fibroblast of skeletal muscle; CL=CL_0011027.
Disease Mouse teratocarcinoma (NCIt: C129859)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129SV ry1(53).
Sex of cell Sex unspecified
Age at sampling Embryo
Category Cancer cell line
Publications

PubMed=9472035; DOI=10.1083/jcb.140.4.831; PMCID=PMC2141739
Feliciano Protasi, Clara Franzini-Armstrong, Paul Denney Allen;
Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle.
J. Cell Biol. 140:831-842(1998)

PubMed=9472036; DOI=10.1083/jcb.140.4.843; PMCID=PMC2141755
Richard A. Moore, Hanh Nguyen, Juan Galceran, Isaac N. Pessah, Paul Denney Allen;
A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function.
J. Cell Biol. 140:843-851(1998)

Cross-references
Encyclopedic resources Wikidata; Q111732617
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number7