| Cell line name |
SK-DSRCT2 |
|---|
| Synonyms |
SK-DSRCT-2 |
|---|
| Accession |
CVCL_B5EG |
|---|
| Resource Identification Initiative |
To cite this cell line use: SK-DSRCT2 (RRID:CVCL_B5EG) |
|---|
| Comments |
Doubling time: 59.5 hours (PubMed=34841430).
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916. |
|---|
| Sequence variations |
- Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:12796; WT1; Name(s)=EWSR1-WT1, EWS-WT1; Note=EWSR1 Ex9-WT1 Ex8 fusion (PubMed=34841430).
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Asn564Asp (c.1690A>G); ClinVar=VCV000376261; Zygosity=Unspecified (PubMed=34841430).
- Mutation; HGNC; HGNC:9949; RECQL4; Simple; p.Val767Glyfs*76; Zygosity=Unspecified (PubMed=34841430).
|
|---|
| Disease |
Adult desmoplastic small round cell tumor (NCIt: C27373)
Desmoplastic small round cell tumor (ORDO: Orphanet_83469) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
20Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=34841430; DOI=10.1242/dmm.047621; PMCID=PMC8807576
Roger S. Smith, Igor Odintsov, Ze-Bing Liu, Allan Jo-Weng Lui, Takuo Hayashi, Morana Vojnic, Yoshiyuki Suehara, Lukas Delasos, Marissa S. Mattar, Julija Hmeljak, Hillary A. Ramirez ...Show all 27 authors... , Melissa Shaw, Gabrielle Bui, Alifiani Bonita Hartono, Eric Gladstone, Siddharth Kunte, Heather Magnan, Inna Khodos, Elisa de Stanchina, Michael P. La Quaglia, Jin-Juan Yao, Marick Lae, Sean B. Lee, Lee Spraggon, Christine A. Pratilas, Marc Ladanyi, Romel Somwar; Show fewer authors
Novel patient-derived models of desmoplastic small round cell tumor enable validation of ERBB signaling as a potential therapeutic vulnerability.
Dis. Model. Mech. 15:dmm047621.1-dmm047621.15(2022) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_B5EG
|
|---|
| Encyclopedic resources |
Wikidata; Q110433230
|
|---|
| Entry history |
|---|
| Entry creation | 16-Dec-2021 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 7 |
|---|
