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Cellosaurus SK-DSRCT1 (CVCL_B5EF)

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Cell line name SK-DSRCT1
Synonyms SK-DSRCT-1
Accession CVCL_B5EF
Resource Identification Initiative To cite this cell line use: SK-DSRCT1 (RRID:CVCL_B5EF)
Comments Doubling time: 23.4 hours (PubMed=34841430).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:12796; WT1; Name(s)=EWSR1-WT1, EWS-WT1; Note=EWSR1 Ex10-WT1 Ex8 fusion (PubMed=34841430).
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Met1634Ter (c.4899delC); Zygosity=Unspecified (PubMed=34841430).
Disease Adult desmoplastic small round cell tumor (NCIt: C27373)
Desmoplastic small round cell tumor (ORDO: Orphanet_83469)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 21Y
Category Cancer cell line
Publications

PubMed=34841430; DOI=10.1242/dmm.047621; PMCID=PMC8807576
Roger S. Smith, Igor Odintsov, Ze-Bing Liu, Allan Jo-Weng Lui, Takuo Hayashi, Morana Vojnic, Yoshiyuki Suehara, Lukas Delasos, Marissa S. Mattar, Julija Hmeljak, Hillary A. Ramirez ...Show all 27 authors... , Melissa Shaw, Gabrielle Bui, Alifiani Bonita Hartono, Eric Gladstone, Siddharth Kunte, Heather Magnan, Inna Khodos, Elisa de Stanchina, Michael P. La Quaglia, Jin-Juan Yao, Marick Lae, Sean B. Lee, Lee Spraggon, Christine A. Pratilas, Marc Ladanyi, Romel Somwar; Show fewer authors
Novel patient-derived models of desmoplastic small round cell tumor enable validation of ERBB signaling as a potential therapeutic vulnerability.
Dis. Model. Mech. 15:dmm047621.1-dmm047621.15(2022)

Cross-references
Encyclopedic resources Wikidata; Q110433229
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number6