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Cellosaurus U2OS RAD52 KO clone #2 (CVCL_B5DD)

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Cell line name U2OS RAD52 KO clone #2
Accession CVCL_B5DD
Resource Identification Initiative To cite this cell line use: U2OS RAD52 KO clone #2 (RRID:CVCL_B5DD)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9824; RAD52.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=30673617; DOI=10.1016/j.celrep.2018.12.102; PMCID=PMC6366628
Jia-Min Zhang, Tribhuwan Yadav, Jian Ouyang, Li Lan, Lee Zou;
Alternative lengthening of telomeres through two distinct break-induced replication pathways.
Cell Rep. 26:955-968.e3(2019)

Cross-references
Encyclopedic resources Wikidata; Q110433300
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number6