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Cellosaurus NIZEDSM1iD21-C7 (CVCL_B4ZR)

[Text version]
Cell line name NIZEDSM1iD21-C7
Synonyms D21C7
Accession CVCL_B4ZR
Resource Identification Initiative To cite this cell line use: NIZEDSM1iD21-C7 (RRID:CVCL_B4ZR)
Comments Karyotypic information: Disomic Chr21 cell line that originate from a mosaic Down syndrome individual.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B4ZP (CM05287)
Age at sampling Adult
Category Induced pluripotent stem cell
Publications

PubMed=25694335; DOI=10.1002/stem.1968; PMCID=PMC4737213
Aoife Murray, Audrey Letourneau, Claudia Canzonetta, Elisavet Stathaki, Stefania Gimelli, Frederique Sloan-Bena, Robert Abrehart, Pollyanna Goh, Shuhui Lim, Chiara Baldo, Franca Dagna-Bricarelli ...Show all 22 authors... , Saad Hannan, Martin Mortensen, David Ballard, Denise Syndercombe-Court, Noemi Fusaki, Mamoru Hasegawa, Trevor Graeme Smart, Cleo Bishop, Stylianos E. Antonarakis, Jurgen Groet, Dean Nizetic; Show fewer authors
Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic Down syndrome model accelerated neuronal ageing and neurodegeneration.
Stem Cells 33:2077-2084(2015)

Cross-references
Encyclopedic resources Wikidata; Q110433099
Entry history
Entry creation16-Dec-2021
Last entry update29-Jun-2023
Version number4