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Cellosaurus BEP2D H2BT (CVCL_B4J2)

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Cell line name BEP2D H2BT
Synonyms H2BT
Accession CVCL_B4J2
Resource Identification Initiative To cite this cell line use: BEP2D H2BT (RRID:CVCL_B4J2)
Comments Characteristics: Tumorigenic in nude mice.
Karyotypic information: Has lost chromosome Y (PubMed=9214610).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Transformant: NCIt; C16279; Alpha radiation.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B4J0 (BEP2D H2B)
Children:
CVCL_B4J3 (BEP2D H2BT2L)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=9214610; DOI=10.1093/carcin/18.6.1251
David A. Weaver, Tom K. Hei, Bharati Hukku, J.A. McRaven, James C. Willey;
Cytogenetic and molecular genetic analysis of tumorigenic human bronchial epithelial cells induced by radon alpha particles.
Carcinogenesis 18:1251-1257(1997)

PubMed=10426802; DOI=10.1093/carcin/20.8.1529
Chang Q. Piao, James C. Willey, Tom K. Hei;
Alterations of p53 in tumorigenic human bronchial epithelial cells correlate with metastatic potential.
Carcinogenesis 20:1529-1533(1999)

Cross-references
Encyclopedic resources Wikidata; Q110432606
Entry history
Entry creation16-Dec-2021
Last entry update10-Apr-2025
Version number6