Cellosaurus cell line KK125 (CVCL

Cellosaurus KK125 (CVCL_B495)

Cross-references
Cell line name	KK125
Synonyms	KK 125
Accession	CVCL_B495
Resource Identification Initiative	To cite this cell line use: KK125 (RRID:CVCL_B495)
Comments	Caution: It is possible that KK124 (Cellosaurus=CVCL_N704) and KK125 are the same cell line. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=2052620).
Disease	Burkitt lymphoma (NCIt: C2912) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_N704 ! KK124
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=2052620; DOI=10.1073/pnas.88.12.5413; PMCID=PMC51883 Gianluca Gaidano, Paola Ballerini, Jerry Z. Gong, Giorgio Inghirami, Antonino Neri, Elizabeth W. Newcomb, Ian Trevor Magrath, Daniel M. Knowles, Riccardo Dalla-Favera; p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 88:5413-5417(1991) PubMed=9473234; DOI=10.1182/blood.V91.5.1680 Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman; p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma. Blood 91:1680-1687(1998)
Cell line databases/resources	cancercelllines; CVCL_B495
Encyclopedic resources	Wikidata; Q54899979
Polymorphism and mutation databases	Cosmic; 931126 IARC_TP53; 168
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	17