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Cellosaurus YUSIK (CVCL_B487)

[Text version]
Cell line name YUSIK
Accession CVCL_B487
Resource Identification Initiative To cite this cell line use: YUSIK (RRID:CVCL_B487)
Comments Part of: Yale University (YU) melanoma cell collection.
Omics: Genomics; Whole exome sequencing.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=20149136; DOI=10.1111/j.1755-148X.2010.00685.x; PMCID=PMC2848976
Halaban R., Zhang W., Bacchiocchi A., Cheng E., Parisi F., Ariyan S., Krauthammer M., McCusker J.P., Kluger Y., Sznol M.
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
Pigment Cell Melanoma Res. 23:190-200(2010)

PubMed=21543894; DOI=10.4161/cc.10.11.15777; PMCID=PMC3233487
Chan E., Patel R., Nallur S., Ratner E., Bacchiocchi A., Hoyt K., Szpakowski S., Godshalk S.E., Ariyan S., Sznol M., Halaban R., Krauthammer M., Tuck D., Slack F.J., Weidhaas J.B.
MicroRNA signatures differentiate melanoma subtypes.
Cell Cycle 10:1845-1852(2011)

PubMed=21569352; DOI=10.1186/1471-2164-12-230; PMCID=PMC3114747
Parisi F., Ariyan S., Narayan D., Bacchiocchi A., Hoyt K., Cheng E., Xu F., Li P.-N., Halaban R., Kluger Y.
Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.
BMC Genomics 12:230.1-230.14(2011)

PubMed=22842228; DOI=10.1038/ng.2359; PMCID=PMC3432702
Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A., McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M., Ariyan S., Narayan D., Dutton-Regester K., Capatana A., Holman E.C., Bosenberg M.W., Sznol M., Kluger H.M., Brash D.E., Stern D.F., Materin M.A., Lo R.S., Mane S.M., Ma S.-G., Kidd K.K., Hayward N.K., Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat. Genet. 44:1006-1014(2012)

PubMed=23012583; PMCID=PMC3447199
Parisi F., Micsinai M., Strino F., Ariyan S., Narayan D., Bacchiocchi A., Cheng E., Xu F., Li P.-N., Kluger H.M., Halaban R., Kluger Y.
Integrated analysis of tumor samples sheds light on tumor heterogeneity.
Yale J. Biol. Med. 85:347-361(2012)

PubMed=26214590; DOI=10.1038/ng.3361; PMCID=PMC4916843
Krauthammer M., Kong Y., Bacchiocchi A., Evans P., Pornputtapong N., Wu C., McCusker J.P., Ma S.-G., Cheng E., Straub R., Serin M., Bosenberg M.W., Ariyan S., Narayan D., Sznol M., Kluger H.M., Mane S.M., Schlessinger J., Lifton R.P., Halaban R.
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.
Nat. Genet. 47:996-1002(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B487
Encyclopedic resources Wikidata; Q54995799
Polymorphism and mutation databases Cosmic; 1548874
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number22