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Cellosaurus YURIF (CVCL_B485)

[Text version]
Cell line name YURIF
Accession CVCL_B485
Resource Identification Initiative To cite this cell line use: YURIF (RRID:CVCL_B485)
Comments Part of: Yale University (YU) melanoma cell collection.
Omics: Genomics; Whole exome sequencing.
Derived from site: Metastatic; Thigh, hypodermis; UBERON=UBERON_0000376+UBERON_0002072.
Sequence variations
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): Technion Genomics Center

Markers:
AmelogeninX,Y
CSF1PO10,13
D3S135815,18
D5S81811,12
D7S82010
D8S117910,13
D13S31711,14
D16S53912
D18S5113,16
D21S1128,30
FGA22,23
Penta D11,12
Penta E11,14
TH016
TPOX8,11
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=20149136; DOI=10.1111/j.1755-148X.2010.00685.x; PMCID=PMC2848976
Ruth Halaban, Wen-Geng Zhang, Antonella Bacchiocchi, Elaine Cheng, Fabio Parisi, Stephan Ariyan, Michael Krauthammer, James Patricia McCusker, Yuval Kluger, Mario Sznol;
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
Pigment Cell Melanoma Res. 23:190-200(2010)

PubMed=21543894; DOI=10.4161/cc.10.11.15777; PMCID=PMC3233487
Elcie Chan, Rajeshvari Patel, Sunitha Nallur, Elena Ratner, Antonella Bacchiocchi, Kathleen Hoyt, Sebastian Szpakowski, Sirie E. Godshalk, Stephan Ariyan, Mario Sznol, Ruth Halaban ...Show all 15 authors... , Michael Krauthammer, David Tuck, Frank J. Slack, Joanne Barnes Weidhaas; Show fewer authors
MicroRNA signatures differentiate melanoma subtypes.
Cell Cycle 10:1845-1852(2011)

PubMed=21569352; DOI=10.1186/1471-2164-12-230; PMCID=PMC3114747
Fabio Parisi, Stephan Ariyan, Deepak Narayan, Antonella Bacchiocchi, Kathleen Hoyt, Elaine Cheng, Fang Xu, Pei-Ning Li, Ruth Halaban, Yuval Kluger;
Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.
BMC Genomics 12:230.1-230.14(2011)

PubMed=22842228; DOI=10.1038/ng.2359; PMCID=PMC3432702
Michael Krauthammer, Yong Kong, Byung Hak Ha, Perry Evans, Antonella Bacchiocchi, James Patricia McCusker, Elaine Cheng, Matthew J. Davis, Gerald Goh, Murim Choi, Stephan Ariyan ...Show all 30 authors... , Deepak Narayan, Ken Dutton-Regester, Ana Capatana, Edna C. Holman, Marcus W. Bosenberg, Mario Sznol, Harriet Margot Kluger, Douglas E. Brash, David F. Stern, Miguel Angel Materin, Roger S. Lo, Shrikant M. Mane, Shuang-Ge Ma, Kenneth Kay Kidd, Nicholas K. Hayward, Richard Priestley Lifton, Joseph Schlessinger, Titus J. Boggon, Ruth Halaban; Show fewer authors
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat. Genet. 44:1006-1014(2012)

PubMed=23012583; PMCID=PMC3447199
Fabio Parisi, Mariann Micsinai, Francesco Strino, Stephan Ariyan, Deepak Narayan, Antonella Bacchiocchi, Elaine Cheng, Fang Xu, Pei-Ning Li, Harriet Margot Kluger, Ruth Halaban, Yuval Kluger;
Integrated analysis of tumor samples sheds light on tumor heterogeneity.
Yale J. Biol. Med. 85:347-361(2012)

PubMed=26214590; DOI=10.1038/ng.3361; PMCID=PMC4916843
Michael Krauthammer, Yong Kong, Antonella Bacchiocchi, Perry Evans, Natapol Pornputtapong, Cen Wu, James Patricia McCusker, Shuang-Ge Ma, Elaine Cheng, Robert Straub, Merdan Serin ...Show all 20 authors... , Marcus W. Bosenberg, Stephan Ariyan, Deepak Narayan, Mario Sznol, Harriet Margot Kluger, Shrikant M. Mane, Joseph Schlessinger, Richard Priestley Lifton, Ruth Halaban; Show fewer authors
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.
Nat. Genet. 47:996-1002(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B485
Encyclopedic resources Wikidata; Q54995788
Polymorphism and mutation databases Cosmic; 1197391
Cosmic; 1548870
Cosmic; 2013572
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number24