| Publications | PubMed=20149136; DOI=10.1111/j.1755-148X.2010.00685.x; PMCID=PMC2848976
Ruth Halaban, Wen-Geng Zhang, Antonella Bacchiocchi, Elaine Cheng, Fabio Parisi, Stephan Ariyan, Michael Krauthammer, James Patricia McCusker, Yuval Kluger, Mario Sznol;
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
Pigment Cell Melanoma Res. 23:190-200(2010) PubMed=21521745; DOI=10.1158/1541-7786.MCR-10-0512; PMCID=PMC3117976
Kathryn Tworkoski, Garima Singhal, Sebastian Szpakowski, Christina Ivins Zito, Antonella Bacchiocchi, Viswanathan Muthusamy, Marcus W. Bosenberg, Michael Krauthammer, Ruth Halaban, David F. Stern;
Phosphoproteomic screen identifies potential therapeutic targets in melanoma.
Mol. Cancer Res. 9:801-812(2011) PubMed=21543894; DOI=10.4161/cc.10.11.15777; PMCID=PMC3233487
Elcie Chan, Rajeshvari Patel, Sunitha Nallur, Elena Ratner, Antonella Bacchiocchi, Kathleen Hoyt, Sebastian Szpakowski, Sirie E. Godshalk, Stephan Ariyan, Mario Sznol, Ruth Halaban ...Show all 15 authors... , Michael Krauthammer, David Tuck, Frank J. Slack, Joanne Barnes Weidhaas; Show fewer authors
MicroRNA signatures differentiate melanoma subtypes.
Cell Cycle 10:1845-1852(2011) PubMed=21569352; DOI=10.1186/1471-2164-12-230; PMCID=PMC3114747
Fabio Parisi, Stephan Ariyan, Deepak Narayan, Antonella Bacchiocchi, Kathleen Hoyt, Elaine Cheng, Fang Xu, Pei-Ning Li, Ruth Halaban, Yuval Kluger;
Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.
BMC Genomics 12:230.1-230.14(2011) PubMed=22842228; DOI=10.1038/ng.2359; PMCID=PMC3432702
Michael Krauthammer, Yong Kong, Byung Hak Ha, Perry Evans, Antonella Bacchiocchi, James Patricia McCusker, Elaine Cheng, Matthew J. Davis, Gerald Goh, Murim Choi, Stephan Ariyan ...Show all 30 authors... , Deepak Narayan, Ken Dutton-Regester, Ana Capatana, Edna C. Holman, Marcus W. Bosenberg, Mario Sznol, Harriet Margot Kluger, Douglas E. Brash, David F. Stern, Miguel Angel Materin, Roger S. Lo, Shrikant M. Mane, Shuang-Ge Ma, Kenneth Kay Kidd, Nicholas K. Hayward, Richard Priestley Lifton, Joseph Schlessinger, Titus J. Boggon, Ruth Halaban; Show fewer authors
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat. Genet. 44:1006-1014(2012) PubMed=23012583; PMCID=PMC3447199
Fabio Parisi, Mariann Micsinai, Francesco Strino, Stephan Ariyan, Deepak Narayan, Antonella Bacchiocchi, Elaine Cheng, Fang Xu, Pei-Ning Li, Harriet Margot Kluger, Ruth Halaban, Yuval Kluger;
Integrated analysis of tumor samples sheds light on tumor heterogeneity.
Yale J. Biol. Med. 85:347-361(2012) |
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