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Cellosaurus IIB-BR-G (CVCL_B410)

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Cell line name IIB-BR-G
Synonyms Instituto de Investigaciones Bioquimicas-BReast cancer-G
Accession CVCL_B410
Resource Identification Initiative To cite this cell line use: IIB-BR-G (RRID:CVCL_B410)
Comments Population: Caucasian.
Doubling time: ~30 hours (PubMed=1661624).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_T742 (IIB-BR-G-MT)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=1661624; DOI=10.1007/BF01975204
Laura C. Bover, Maria Marcela Barrio, Irma Slavutsky, Alicia Ines Bravo, Carlos Quintans, Ana Bagnati, Baltasar Lema, Jorge Schiaffi, Roberto Yomha, Jose Mordoh;
Description of a new human breast cancer cell line, IIB-BR-G, established from a primary undifferentiated tumor.
Breast Cancer Res. Treat. 19:47-56(1991)

PubMed=9620446
Laura C. Bover, Maria Marcela Barrio, Alicia Ines Bravo, Irma Slavutsky, Irene Larripa, Arquimedes Bolondi, Miguel Ayala, Jose Mordoh;
The human breast cancer cell line IIB-BR-G has amplified c-myc and c-fos oncogenes in vitro and is spontaneously metastatic in vivo.
Cell. Mol. Biol. 44:493-504(1998)

PubMed=21308409; DOI=10.1007/s10549-011-1360-2
Maria P. Roberti, Maria Marcela Barrio, Alicia Ines Bravo, Yamila S. Rocca, Juan Martin Arriaga, Michele Bianchini, Jose Mordoh, Estrella M. Levy;
IL-15 and IL-2 increase cetuximab-mediated cellular cytotoxicity against triple negative breast cancer cell lines expressing EGFR.
Breast Cancer Res. Treat. 130:465-475(2011)

Cross-references
Encyclopedic resources Wikidata; Q54897420
Polymorphism and mutation databases Cosmic; 1507366
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number11