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Cellosaurus PEO1X (CVCL_B3UQ)

[Text version]

Cell line name PEO1X
Accession CVCL_B3UQ
Resource Identification Initiative To cite this cell line use: PEO1X (RRID:CVCL_B3UQ)
Comments Doubling time: 47.84 hours (CelloPub=CLPUB00667).
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Sequence variations
  • Mutation; HGNC; 1101; BRCA2; Simple; p.Tyr1655Ter (c.4965C>G) (5193C>G); ClinVar=VCV000037936; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly244Asp (c.731G>A); ClinVar=VCV000372785; Zygosity=Unspecified (CelloPub=CLPUB00667).
Disease BRCA2 syndrome (NCIt: C36101)
Ovarian cystadenocarcinoma (NCIt: C5228)
Hereditary breast and ovarian cancer syndrome (ORDO: Orphanet_145)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2686 (PEO1)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

CLPUB00667
Lisio M.-A.
Evaluation of platinum-sensitivity in a cell line model of high grade serous ovarian cancer and the induction of resistance from a chemo- sensitive cell line through the repopulation of cells following short-term cisplatin treatment.
Thesis PhD (2019), McGill University Montreal, Canada

Cross-references
Encyclopedic resources Wikidata; Q110433135
Entry history
Entry creation16-Dec-2021
Last entry update17-Mar-2022
Version number2