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Cellosaurus PEO1X (CVCL_B3UQ)

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Cell line name PEO1X
Accession CVCL_B3UQ
Resource Identification Initiative To cite this cell line use: PEO1X (RRID:CVCL_B3UQ)
Comments Population: Caucasian.
Doubling time: 47.84 hours (CelloPub=CLPUB00667).
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Tyr1655Ter (c.4965C>G) (5193C>G); ClinVar=VCV000037936; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly244Asp (c.731G>A); ClinVar=VCV000372785; Zygosity=Unspecified (CelloPub=CLPUB00667).
Disease BRCA2 syndrome (NCIt: C36101)
Ovarian cystadenocarcinoma (NCIt: C5228)
Hereditary breast and ovarian cancer syndrome (ORDO: Orphanet_145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2686 (PEO1)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

CLPUB00667
Michael-Anthony Lisio;
Evaluation of platinum-sensitivity in a cell line model of high grade serous ovarian cancer and the induction of resistance from a chemo- sensitive cell line through the repopulation of cells following short-term cisplatin treatment.
Thesis PhD (2019); McGill University Montreal; Montreal; Canada

Cross-references
Cell line databases/resources cancercelllines; CVCL_B3UQ
Encyclopedic resources Wikidata; Q110433135
Entry history
Entry creation16-Dec-2021
Last entry update10-Apr-2025
Version number7