Cellosaurus cell line HCC827-Luc-mCh-Puro (CVCL

Cross-references
Cell line name	HCC827-Luc-mCh-Puro
Accession	CVCL_B3SC
Resource Identification Initiative	To cite this cell line use: HCC827-Luc-mCh-Puro (RRID:CVCL_B3SC)
Comments	Population: Caucasian. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2236_2250del15); ClinVar=VCV000177620; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val218del (c.646_648GTG[2]) (c.652_654delGTG); ClinVar=VCV000634761; Zygosity=Homozygous (from parent cell line).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_2063 (HCC827)
Sex of cell	Female
Age at sampling	39Y
Category	Cancer cell line
Web pages	Provider; Creative Biolabs; IOC-ZP160; https://www.creative-biolabs.com/immuno-oncology/cellonco-human-hcc827-luc-mch-puro-reporter-tumor-cell-line-160.htm
Cell line databases/resources	cancercelllines; CVCL_B3SC
Encyclopedic resources	Wikidata; Q110432841
Entry history
Entry creation	16-Dec-2021
Last entry update	14-Aug-2025
Version number	9